Bosch platinum plugs (reg, +2, +4) have worked very well for me in newer cars, not so well in those older than about 1999. They like higher voltage ignition systems. They can misfire with lower voltage. Sometimes larger plug wires fix it, it depends on the overall design of the ignition system.Despite the hype on the web and anecdotal stories, virtually all spark plug manufacturers recommend against using anti-seize compound when installing plugs. They nickle-plate the threads to protect against seizing. The anti-seize compounds, even copper based, tend to increase the resistance to ground, and to upset the torque required to seat the plugs. The silver based compound will seriously increase resistance causing misfires and serious overheating of the plugs, and I have experienced the plug ceramic tips breaking off and falling into the cylinder. It sounds like a bad valve lifter and can damage the cylinder or valves. Copper based compound is less resistance, but still often...